SCHEMBL6265653

SCHEMBL6265653

O=c1oc(=O)oc2c(ccc3c2ccc2oc(=O)oc(=O)oc23)o1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.36
MAOA P21397 6/20 0.36
MAPT P10636 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
PGAM1 P18669 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GFER P55789 1/20 0.35
ATP1A1 P05023 1/20 0.35
ATP1B1 P05026 1/20 0.35
ATP1A3 P13637 1/20 0.35
ATP1B2 P14415 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744044 0.98 ESR2 (0.35) ESR2MAOAMAPTSMN1; SMN2KDM4E
SCHEMBL5706548 0.87 MAPT (0.35) ESR2MAOAMAPTSMN1; SMN2KDM4E
SCHEMBL8744105 0.81 MAPT (0.34) ESR2MAOAMAPTSMN1; SMN2KDM4E
SCHEMBL856949 0.75 MAOA (0.38) ESR2MAOAMAPTSMN1; SMN2KDM4E
SCHEMBL9858230 0.71 AHR (0.41) MAOAMAOBCYP1A2AHR
SCHEMBL29441848 0.71 CLK1 (0.37) MAOAMAPTSMN1; SMN2KDM4EHPGD
SCHEMBL8762664 0.70 MAOA (0.47) ESR2MAOAMAPTSMN1; SMN2KDM4E
SCHEMBL16612995 0.70 MAOA (0.46) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL14188315 0.67 ESR2 (0.38) ESR2MAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL10887347 0.67 MAOA (0.32) ESR2MAOAESR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1054031-B1 Increasing the molecular weight and modification of condensation polymers CIBA SC HOLDING AG (CH) 2005-08-24 EP claimed
EP-0768559-B1 Active-matrix liquid crystal displays with polyimide alignment films from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines DU PONT (US) 2003-08-13 EP claimed
EP-1054031-A2 Increasing the molecular weight and modification of condensation polymers Ciba SC Holding AG (CH) 2000-11-22 EP claimed
EP-0356172-B1 Epoxy resins containing imido rings, production process thereof, and epoxy resin compositions containing the same MITSUI TOATSU CHEMICALS (JP) 1997-01-15 EP claimed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
EP-1568733-A1 Porous inorganic filler particles having an organopolysiloxane coating for use in curable casting compositions ABB RESEARCH LTD. (CH) 2005-08-31 EP disclosed
EP-1054031-B1 Increasing the molecular weight and modification of condensation polymers CIBA SC HOLDING AG (CH) 2005-08-24 EP disclosed
EP-1331234-B1 Potting composition based on duroplastic epoxid resin ABB RESEARCH LTD (CH) 2004-09-22 EP disclosed
EP-1091992-B1 RESIN SYSTEM ABB SCHWEIZ AG (CH) 2003-12-03 EP disclosed
EP-1354916-A1 Self-hardening epoxy resin for the manufacture of electric insulators ABB RESEARCH LTD. (CH) 2003-10-22 EP disclosed
EP-1336642-A1 Self-healing potting compositions for the production of electrical isolations ABB RESEARCH LTD. (CH) 2003-08-20 EP disclosed
EP-1331234-A1 Potting composition based on duroplastic epoxid resin ABB Research Ltd. (CH) 2003-07-30 EP disclosed
EP-0390803-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES Chemie Linz Gesellschaft m.b.H. (AT) 1990-10-10 EP disclosed
EP-0386088-A1 NEW SOLUBLE AND/OR MELTABLE POLYAMIDE-POLYAMIDE, POLYAMIDE-POLYAMIDEIMIDE AND POLYAMIDE-POLYIMIDE BLOCK COPOLYMERS Chemie Linz Gesellschaft m.b.H. (AT) 1990-09-12 EP disclosed
WO-1989004337-A1 NEW SOLUBLE AND/OR MELTABLE POLYAMIDE-POLYAMIDE, POLYAMIDE-POLYAMIDEIMIDE AND POLYAMIDE-POLYIMIDE BLOCK COPOLYMERS CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1989-05-18 WO disclosed
WO-1989004298-A1 SULFUR-CONTAINING AROMATIC TETRACARBOXYLIC ACIDS AND THEIR DERIVATIVES CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1989-05-18 WO disclosed
EP-0315992-A1 Sulfur-containing aromatic tetracarboxylic acids and their derivatives Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed
EP-0315993-A1 Soluble and/or fusible block polyamide-polyamides, polyamide-polyamideimides and polyamides-polyimides Chemie Linz Gesellschaft m.b.H. (AT) 1989-05-17 EP disclosed
EP-0300326-A1 Hydroxypolyimides and high temperature resistant positive photoresists HOECHST CELANESE CORPORATION (US) 1989-01-25 EP disclosed