SCHEMBL856949

SCHEMBL856949

O=c1oc(=O)oc2ccc(o1)c1c3ccc(oc(=O)oc(=O)o3)c21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.38
MAPT P10636 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
PGAM1 P18669 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
GFER P55789 1/20 0.37
MGAM O43451 3/20 0.33
GAA P10253 3/20 0.33
SI P14410 2/20 0.33
MGAM2 Q2M2H8 2/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8018963 0.88 MAOA (0.46) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL25121958 0.85 ALDH1A1 (0.38) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL5706548 0.81 MAPT (0.35) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL9858230 0.77 AHR (0.41) MAOALMNACYP1A2
SCHEMBL1662244 0.76 MAPT (0.33) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL16612995 0.75 MAOA (0.46) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL6265653 0.75 ESR2 (0.36) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL339615 0.73 MAOA (0.57) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8744044 0.73 ESR2 (0.35) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL6206429 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3302969-B1 LIGNOCELLULOSIC COMPOSITES AND METHODS OF MAKING SAME COLLABORATIVE AGGREGATES LLC (US) 2021-01-27 EP claimed
EP-2918609-A1 Hydrogenated nitrile rubber containing amino methyl groups containing vulcanisable compositions , process for their vulcanization and vulcanisates obtainable by this process LANXESS Deutschland GmbH (DE) 2015-09-16 EP claimed
EP-2692775-B1 POLYIMIDE, POLYIMIDE-BASED POLYMER ELECTROLYTE MEMBRANE, MEMBRANE- ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL NITTO DENKO CORP (JP) 2015-04-08 EP claimed
EP-1725607-B1 BIODEGRADABLE ALIPHATIC-AROMATIC COPOLYESTER FILMS KIMBERLY CLARK CO (US) 2012-05-09 EP claimed
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP claimed
EP-1336636-B1 Liquid crystal aligning agent,method of forming a liquid crystal alignment film and liquid crystal display element JSR CORP (JP) 2006-05-03 EP claimed
EP-1091992-B1 RESIN SYSTEM ABB SCHWEIZ AG (CH) 2003-12-03 EP claimed
EP-0768559-B1 Active-matrix liquid crystal displays with polyimide alignment films from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines DU PONT (US) 2003-08-13 EP claimed
EP-0902066-B1 Curable coating compositions from oligomeric condensation products BAYER AG (DE) 2003-05-07 EP claimed
EP-0716113-B1 Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof TOHO RAYON KK (JP) 2000-01-19 EP claimed
EP-0855382-A2 Hydrocarbon derivatives modified by fluoroalkyl group Clariant GmbH (DE) 1998-07-29 EP claimed
EP-0419804-B1 Multilayer structures of different electroactive materials and methods of fabrication thereof IBM (US) 1997-12-29 EP claimed
EP-0418889-B1 Polyamic acid having three-dimensional network molecular structure, polyimide obtained therefrom and process for the preparation thereof TOHO RAYON KK (JP) 1997-02-05 EP claimed
EP-0356172-B1 Epoxy resins containing imido rings, production process thereof, and epoxy resin compositions containing the same MITSUI TOATSU CHEMICALS (JP) 1997-01-15 EP claimed
EP-0523240-B1 BISIMIDE COMPOUNDS, POLYIMIDE RESIN COMPOSITION PREPARED THEREFROM, AND CARBON FIBER-REINFORCED POLYIMIDE RESIN COMPOSITION MITSUI TOATSU CHEMICALS (JP) 1996-03-20 EP claimed
EP-0431547-B1 Charge transfer salts and uses thereof IBM (US) 1994-09-21 EP claimed
EP-0033015-B1 ELECTRICALLY CONDUCTIVE CYCLIC POLYIMIDES BAYER AG (DE) 1983-05-04 EP claimed
EP-0033015-A1 Electrically conductive cyclic polyimides BAYER AG (DE) 1981-08-05 EP claimed
EP-2652026-B1 POLYMER COMPOSITION HAVING HEAT-ABSORBING PROPERTIES AND HIGH RESISTANCE TO WEATHERING COVESTRO DEUTSCHLAND AG (DE) 2017-08-02 EP disclosed
EP-0009742-A1 Photoconductive masses based on synthetics and their use in the production of films and composite elements BASF Aktiengesellschaft (DE) 1980-04-16 EP disclosed