SCHEMBL6266567

SCHEMBL6266567

O=c1n(CC(Br)Br)c(=O)n(CC(Br)Br)c(=O)n1CC(Br)Br

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
TP53 P04637 1/20 0.31
HBB P68871 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26874 0.75 ALDH1A1 (0.33)
SCHEMBL95226 0.71 CYP3A4 (0.31) CYP3A4
SCHEMBL10013812 0.63 TSHR (0.39) TP53SMN1; SMN2
SCHEMBL11626556 0.60
SCHEMBL18889151 0.56 CYP3A4 (0.45) CYP3A4TP53HBBSMN1; SMN2
SCHEMBL6265971 0.55 RGS4 (0.32) CYP3A4
SCHEMBL6268023 0.53 CYP3A4 (0.31) CYP3A4
SCHEMBL331903 0.52 PDE4A (0.47) CYP3A4
SCHEMBL446969 0.50
SCHEMBL28935048 0.45

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed