Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267146 | 1.00 | FOLH1 (0.40) | FOLH1L3MBTL1CA12CA1CA2 | |
| SCHEMBL6267990 | 0.88 | CTSV (0.43) | FOLH1L3MBTL1CA12CA1CA2 | |
| SCHEMBL6267993 | 0.88 | CTSV (0.43) | FOLH1L3MBTL1CA12CA1CA2 | |
| SCHEMBL6267511 | 0.88 | FOLH1 (0.39) | FOLH1MEN1KMT2APOLBKCNH2 | |
| SCHEMBL6267508 | 0.88 | FOLH1 (0.39) | FOLH1MEN1KMT2APOLBKCNH2 | |
| SCHEMBL6270670 | 0.87 | LRRK2 (0.39) | FOLH1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6270671 | 0.87 | LRRK2 (0.39) | FOLH1L3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL6269322 | 0.85 | KDM4E (0.41) | L3MBTL1CA12CA1CA2MEN1 | |
| SCHEMBL6269316 | 0.85 | KDM4E (0.41) | L3MBTL1CA12CA1CA2MEN1 | |
| SCHEMBL6273806 | 0.84 | ALOX5 (0.43) | L3MBTL1CA12CA1CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |