Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794662 | 0.79 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL4076379 | 0.79 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL15907070 | 0.76 | TDP1 (0.46) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL19911424 | 0.73 | KMT2A (0.34) | LMNAKMT2AHSD17B10 | |
| SCHEMBL19911326 | 0.73 | FGFR1 (0.50) | TNFFGFR1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL19911408 | 0.73 | MAPT (0.51) | HTTFGFR1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL19848235 | 0.73 | MAPT (0.40) | HTTFGFR1SMN1; SMN2HSD17B10 | |
| SCHEMBL19848669 | 0.73 | DAPK3 (0.40) | FGFR1 | |
| SCHEMBL6209368 | 0.73 | HTT (0.46) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL19848118 | 0.73 | DPP4 (0.35) | CYP11B1CYP11B2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020026059-A1 | Benzimidazole derivatives | ASSMANN LUTZ (DE) | 2002-02-28 | — | — | US | claimed |
| CN-1187820-A | Benzimidazole derivatives | BAYER AG (DE) | 1998-07-15 | — | — | CN | claimed |
| EP-0820457-A1 | BENZIMIDAZOLE DERIVATIVES | BAYER AG (DE) | 1998-01-28 | — | — | EP | claimed |
| WO-1996032395-A1 | BENZIMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-17 | — | — | WO | claimed |
| EP-0230844-A1 | Fungicides comprising triazole and oligo ether groups, and mixtures thereof | RHONE-POULENC AGROCHIMIE (FR) | 1987-08-05 | — | — | EP | claimed |
| US-4490463-A | SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1984-12-25 | — | — | US | claimed |
| US-4223082-A | ELECTROMAGNETIC WAVES | EASTMAN KODAK COMPANY (US) | 1980-09-16 | — | — | US | claimed |
| CN-114213204-B | Method for synthesizing aryl nitrile compound from tert-butyl isonitrile | 浙江工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-114213204-A | Method for synthesizing aryl nitrile compound from tert-butyl isonitrile | 浙江工业大学 | 2022-03-22 | — | — | CN | disclosed |
| US-10756394-B2 | Nonaqueous electrolyte and nonaqueous secondary battery | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-08-25 | — | — | US | disclosed |
| US-10756394-B2 | Nonaqueous electrolyte and nonaqueous secondary battery | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2020-08-25 | — | — | US | disclosed |
| US-10660898-B2 | Benzimidazole derivatives as PI3 kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2020-05-26 | — | — | US | disclosed |
| EP-3467930-B1 | NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY | ASAHI CHEMICAL IND (JP) | 2020-05-13 | — | — | EP | disclosed |
| EP-0584811-B1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (III) | EASTMAN KODAK CO (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5298388-A | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (III) | EASTMAN KODAK COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0584811-A1 | Process for the preparation of a grain stabilized high chloride tabular grain photographic emulsion (III) | EASTMAN KODAK COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0239508-A2 | 2-Cyano-benzimidazole derivatives, their preparation and use as fungicides, their association with other fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-30 | — | — | EP | disclosed |
| EP-0230844-A1 | Fungicides comprising triazole and oligo ether groups, and mixtures thereof | RHONE-POULENC AGROCHIMIE (FR) | 1987-08-05 | — | — | EP | disclosed |
| US-4490463-A | SENSITIZERS | EASTMAN KODAK COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10756394-B2 | Nonaqueous electrolyte and nonaqueous secondary battery | BPTF, BRD4, KCNN2 | TDP1 979/4885HTT 1107/4885CYP11B1 640/4885 |
| US-20020026059-A1 | Benzimidazole derivatives | BAK1, XDH, ZFX | TDP1 2058/4885HTT 4795/4885CYP11B1 1431/4885 |
| US-10660898-B2 | Benzimidazole derivatives as PI3 kinase inhibitors | PI4KB, PIK3CD, PI4KA | TDP1 1700/4885HTT 2110/4885CYP11B1 1504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.