Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151657 | 0.92 | HRH3 (0.40) | KCNA3HPGD | |
| SCHEMBL10614694 | 0.92 | KCNA3 (0.48) | KCNA3 | |
| SCHEMBL9539656 | 0.92 | KCNA3 (0.48) | KCNA3 | |
| SCHEMBL9705568 | 0.92 | KCNA3 (0.48) | KCNA3 | |
| SCHEMBL9705573 | 0.89 | KCNA3 (0.50) | KCNA3 | |
| SCHEMBL4160069 | 0.88 | HRH3 (0.37) | — | |
| SCHEMBL8884778 | 0.86 | PRMT1 (0.46) | KCNA3 | |
| SCHEMBL11035728 | 0.85 | KCNA3 (0.55) | KCNA3 | |
| SCHEMBL9705589 | 0.83 | TRPA1 (0.43) | KCNA3 | |
| SCHEMBL11091678 | 0.82 | KCNA3 (0.57) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-12-22 | — | — | US | disclosed |
| WO-2005094833-A1 | NOVEL N-SUBSTITUTED DIHYDROBENZOTHIEPINO, DIHYDROBENZOXEPINO AND TETRAHYDRO BENZOCYCLOHEPTA INDOLES AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282863-A1 | Novel-N substituted dihydrobenzothiepino, dihydrobenzoxepino and tetrahydro benzocyclohepta indoles as selective estrogen receptor modulators | ESR1, ESR2, HSD17B11 | NPC1 668/4885RAB9A 3661/4885KCNA3 3534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.