Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371494 | 0.92 | LCK (0.58) | LCKHDAC1HDAC6ALDH1A1APP | |
| SCHEMBL28349735 | 0.92 | GAA (0.60) | LCKGAAAPPPKM | |
| SCHEMBL28349736 | 0.92 | GAA (0.60) | LCKGAAAPPPKM | |
| SCHEMBL5378089 | 0.89 | LCK (0.53) | LCKHDAC1HDAC6GAAALDH1A1 | |
| SCHEMBL5371472 | 0.87 | TAS1R3 (0.52) | LCKGAAALDH1A1APPPKM | |
| SCHEMBL18273972 | 0.86 | IAPP (0.51) | LCKGAAALDH1A1APPPKM | |
| SCHEMBL6267583 | 0.86 | LCK (0.70) | LCKHDAC1HDAC6ALDH1A1NPSR1 | |
| SCHEMBL10099849 | 0.86 | LCK (0.62) | LCKHDAC1HDAC6ALDH1A1NPSR1 | |
| SCHEMBL11864242 | 0.85 | LCK (0.68) | LCKHDAC1HDAC6ALDH1A1NPSR1 | |
| SCHEMBL10792638 | 0.85 | LCK (0.71) | LCKHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | claimed |
| EP-1499585-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | Mogam Biotechnology Research Institute (KR) | 2005-01-26 | — | — | EP | disclosed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | disclosed |
| WO-2003089405-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | LCK, SRC, FYN | LCK 1/4885HDAC1 2336/4885HDAC6 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.