Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 15/20 | 0.67 |
| ▸ | THRB | P10828 | 15/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640873 | 0.85 | THRA (0.73) | THRATHRB | |
| SCHEMBL6275877 | 0.85 | THRA (0.66) | THRATHRB | |
| SCHEMBL6271803 | 0.85 | THRA (0.51) | THRATHRB | |
| SCHEMBL6275008 | 0.81 | THRA (0.59) | THRATHRB | |
| SCHEMBL6273741 | 0.77 | THRB (0.42) | THRATHRB | |
| SCHEMBL1642377 | 0.77 | THRA (0.76) | THRATHRB | |
| SCHEMBL6545155 | 0.75 | THRA (0.74) | THRATHRB | |
| SCHEMBL6269426 | 0.72 | THRA (0.56) | THRATHRB | |
| SCHEMBL7069787 | 0.72 | THRA (0.74) | THRATHRB | |
| SCHEMBL328501 | 0.72 | THRB (0.55) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297833-B1 | Indole carboxylic acids as thyroid receptor ligands | PFIZER PROD INC (US) | 2005-12-21 | — | — | EP | claimed |