Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470929 | 0.83 | IDH1 (0.37) | IDH1SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL2674706 | 0.78 | GAA (0.47) | IDH1SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL28472061 | 0.75 | GAA (0.53) | SLC6A2SLC6A4SLC6A3KCNA5TSHR | |
| SCHEMBL28468764 | 0.75 | GAA (0.57) | SLC6A2SLC6A4SLC6A3KCNA5KCNE1 | |
| SCHEMBL5349302 | 0.73 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3KCNA5TSHR | |
| SCHEMBL28469055 | 0.72 | ADORA2A (0.39) | TP53EGFRCYP1A2CYP3A4ADORA2A | |
| SCHEMBL28464903 | 0.72 | ADORA2A (0.39) | TP53EGFRCYP1A2CYP3A4ADORA2A | |
| SCHEMBL3360610 | 0.72 | ALDH1A1 (0.50) | IDH1SLC6A2SLC6A4SLC6A3KCNA5 | |
| SCHEMBL13081517 | 0.71 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNA5TSHR | |
| SCHEMBL125581 | 0.71 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3KCNA5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601648-A2 | PROCESS FOR PREPARING PYRIDINE-SUBSTITUTED AMINO KETAL DERIVATIVES | Sanofi-Aventis Deutschland GmbH (DE) | 2005-12-07 | — | — | EP | disclosed |
| US-6916934-B2 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-07-12 | — | — | US | disclosed |
| WO-2004072026-A2 | PROCESS FOR PREPARING PYRIDINE-SUBSTITUTED AMINO KETAL DERIVATIVES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040158073-A1 | Process for preparing pyridine-substituted amino ketal derivatives | KMO, PKN1, PKN2 | IDH1 697/4885SLC6A2 4584/4885SLC6A4 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.