Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268030 | 0.93 | SLC6A9 (0.58) | KDM4EMAPTHPGDALDH1A1SLC6A9 | |
| SCHEMBL7676117 | 0.78 | CYP11B2 (0.51) | KDM4EHPGDSLC6A9LMNA | |
| SCHEMBL23886286 | 0.78 | CYP2D6 (0.53) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7678374 | 0.77 | CYP11B2 (0.50) | KDM4EHPGDSLC6A9LMNA | |
| SCHEMBL27450653 | 0.77 | KDM4E (0.55) | KDM4EMAPTHPGDALDH1A1HTR2C | |
| SCHEMBL27965221 | 0.77 | KDM4E (0.55) | KDM4EMAPTHPGDALDH1A1HTR2C | |
| SCHEMBL2261293 | 0.77 | KDM4E (0.55) | KDM4EMAPTHPGDALDH1A1HTR2C | |
| SCHEMBL6268065 | 0.76 | BACE1 (0.57) | KDM4EMAPTHPGDALDH1A1SLC6A9 | |
| SCHEMBL14188914 | 0.74 | HTR2C (0.42) | KDM4EMAPTHPGDALDH1A1HTR2C | |
| SCHEMBL6265943 | 0.74 | KDM4E (0.52) | KDM4EMAPTHPGDALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100301-A1 | 2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |