Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL892322 | 0.87 | LMNA (0.63) | LMNA | |
| SCHEMBL8071352 | 0.82 | LMNA (0.71) | LMNA | |
| SCHEMBL891598 | 0.81 | LMNA (0.55) | LMNA | |
| SCHEMBL891898 | 0.78 | LMNA (0.42) | LMNA | |
| SCHEMBL3206613 | 0.76 | LMNA (0.60) | LMNA | |
| SCHEMBL3199752 | 0.76 | LMNA (0.60) | LMNA | |
| Phosphoric Acid SCHEMBL368038 | 0.75 | LMNA (0.67) | LMNAMEN1CYP1A2KMT2A | |
| SCHEMBL6269115 | 0.73 | — | — | |
| SCHEMBL29077326 | 0.73 | LMNA (0.55) | LMNA | |
| SCHEMBL3453066 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095425-A1 | DITHIOPHOSPHATO-PLATINUM-COMPLEXES FOR THE TREATMENT OF CANCERS | PHARMINOX LIMITED (GB) | 2005-10-13 | — | — | WO | disclosed |