SCHEMBL8071352

SCHEMBL8071352

CCOC(C)OCC.COCCOC

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
THRB P10828 1/20 0.40
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL892322 0.95 LMNA (0.63) LMNATHRBPIK3CD
SCHEMBL3199752 0.92 LMNA (0.60) LMNATHRB
SCHEMBL3206613 0.92 LMNA (0.60) LMNATHRB
SCHEMBL29077326 0.89 LMNA (0.55) LMNATHRBPIK3CD
SCHEMBL891598 0.88 LMNA (0.55) LMNATHRB
SCHEMBL3453066 0.87
SCHEMBL9459 0.84
SCHEMBL2094168 0.84 LMNA (1.00) LMNATHRB
SCHEMBL6269110 0.82 LMNA (0.48) LMNA
Dimethoxymethane SCHEMBL7529172 0.82 LMNA (0.71) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6166093-A Cosmetic or dermatological compositions of polyurethane and/or polyurea block polycondensation products containing silicone grafts and their use L'OREAL (FR) 2000-12-26 US disclosed