Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786070 | 0.80 | LMNA (0.65) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL6269506 | 0.79 | AKR1B10 (0.49) | LMNATDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL6267530 | 0.79 | LMNA (0.54) | LMNATDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL13504627 | 0.79 | LMNA (0.63) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL20774557 | 0.78 | LMNA (0.61) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL20774563 | 0.77 | LMNA (0.59) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL571296 | 0.77 | LMNA (0.59) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL11598763 | 0.77 | LMNA (0.69) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL1869078 | 0.76 | LMNA (0.79) | LMNATDP1TSHRMAPK1CYP1A2 | |
| SCHEMBL28978386 | 0.76 | LMNA (0.79) | LMNATDP1TSHRMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103061-A1 | METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS | DOW CORNING TORAY CO., LTD. (JP) | 2005-11-03 | — | — | WO | disclosed |