Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268774 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALOX15ALDH1A1 | |
| SCHEMBL6269445 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1ALOX15ALDH1A1 | |
| SCHEMBL6266974 | 0.76 | ALDH1A1 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL6268777 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ANPC1ALOX15ALDH1A1 | |
| SCHEMBL6271786 | 0.73 | NPC1 (0.45) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL3981602 | 0.73 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT | |
| SCHEMBL6266832 | 0.73 | GAA (0.40) | RAB9AALOX15ALDH1A1HPGDTDP1 | |
| SCHEMBL3987725 | 0.73 | RAB9A (0.44) | SMN1; SMN2RAB9ANPC1ALOX15ALDH1A1 | |
| SCHEMBL3982707 | 0.71 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1ALOX15ALDH1A1 | |
| SCHEMBL6268131 | 0.70 | ALDH1A1 (0.38) | SMN1; SMN2RAB9ANPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |