Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB4 | Q16877 | 7/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 6/20 | 0.44 |
| ▸ | CMA1 | P23946 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684828 | 0.86 | PFKFB4 (0.41) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3695390 | 0.83 | PPARD (0.43) | PFKFB4PFKFB3CMA1 | |
| SCHEMBL3685095 | 0.80 | PPARA (0.49) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL6269039 | 0.79 | HTR6 (0.42) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3689304 | 0.79 | PFKFB3 (0.41) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3687431 | 0.79 | PFKFB3 (0.41) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3695828 | 0.77 | CMA1 (0.43) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3679313 | 0.76 | PFKFB3 (0.43) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3683554 | 0.76 | PPARD (0.44) | PFKFB4PFKFB3CMA1HTR6 | |
| SCHEMBL3681379 | 0.76 | PPARD (0.41) | PFKFB4PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597248-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073606-A2 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |