Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83396 | 0.87 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1LMNAUSP2 | |
| SCHEMBL3458647 | 0.81 | HTR2A (0.54) | KDM4EALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3073525 | 0.80 | NAMPT (0.47) | KDM4EHSD17B10ALDH1A1LMNAUSP2 | |
| SCHEMBL7672874 | 0.77 | CHRNA7 (0.57) | ALDH1A1LMNACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL6271049 | 0.75 | OPRL1 (0.46) | ALDH1A1LMNACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL82729 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3458409 | 0.74 | ALDH1A1 (0.63) | KDM4EALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3458346 | 0.73 | DRD2 (0.54) | ALDH1A1PTAFR | |
| SCHEMBL5557428 | 0.73 | DRD2 (0.48) | ALDH1A1LMNACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL3077208 | 0.72 | FNTA (0.47) | ALDH1A1CYP2C9CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079832-B1 | USE OF VITAMIN PP COMPOUNDS | KLINGE CO CHEM PHARM FAB (DE) | 2005-11-30 | — | — | EP | claimed |