Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567503 | 0.86 | NOTUM (0.59) | NOTUMTNFNOD2NOD1ALDH1A1 | |
| SCHEMBL6805438 | 0.85 | ALDH1A1 (0.53) | NOTUMTNFNOD2NOD1ALDH1A1 | |
| SCHEMBL8570195 | 0.83 | NOTUM (0.56) | NOTUMTNFNOD2NOD1ALDH1A1 | |
| SCHEMBL6287462 | 0.80 | KDM4E (0.39) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL26079156 | 0.78 | NOTUM (0.64) | NOTUMTNFNOD2NOD1PKLR | |
| SCHEMBL26072334 | 0.77 | NOTUM (0.52) | NOTUMALDH1A1POLBSMN1; SMN2PKLR | |
| SCHEMBL30366343 | 0.77 | MAPK1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7416927 | 0.77 | NOTUM (0.62) | NOTUMTNFNOD2NOD1SMN1; SMN2 | |
| SCHEMBL32673424 | 0.77 | NOTUM (0.62) | NOTUMTNFNOD2NOD1ALDH1A1 | |
| SCHEMBL26071790 | 0.77 | NOTUM (0.62) | NOTUMTNFNOD2NOD1PKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161418-B1 | 1-ACYL-7-NITROINDOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PHOTOCLEAVABLE PRECURSORS | MEDICAL RES COUNCIL (GB) | 2005-12-28 | — | — | EP | disclosed |
| US-6765014-B1 | DRUG DELIVERY OF NEUROACTIVE AMINO ACIDS OR METAL CHELATORS | MEDICAL RESEARCH COUNCIL (GB) | 2004-07-20 | — | — | US | disclosed |