Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639346 | 0.99 | LMNA (0.46) | LMNAALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL6268901 | 0.94 | LMNA (0.44) | LMNAALDH1A1KDM4EHTTL3MBTL1 | |
| SCHEMBL27441898 | 0.87 | ALDH1A1 (0.45) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27441895 | 0.87 | ALDH1A1 (0.45) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL6253936 | 0.86 | LMNA (0.44) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27489532 | 0.83 | KDM4E (0.42) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27639303 | 0.83 | KDM4E (0.42) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL6267847 | 0.82 | LMNA (0.40) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27463399 | 0.82 | LMNA (0.40) | LMNAALDH1A1KDM4EHTTMAPT | |
| SCHEMBL27463835 | 0.81 | KDM4E (0.39) | LMNAALDH1A1KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |