Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | BCR | P11274 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | GALR1 | P47211 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4839029 | 0.88 | GALR1 (0.46) | FGFR3CDK4CCND1KCNH2BCL6 | |
| SCHEMBL4836499 | 0.86 | IDH2 (0.43) | AXLFGFR3CDK4CDK6CCNT1 | |
| SCHEMBL6820022 | 0.82 | CCNA2 (0.42) | AXLCDK4CCND3 | |
| SCHEMBL6916773 | 0.82 | AXL (0.40) | AXLFGFR3CDK4CDK6ABL1 | |
| SCHEMBL4832446 | 0.80 | GALR1 (0.42) | AXLFGFR3KCNH2BCL6GALR2 | |
| SCHEMBL27628528 | 0.80 | AGPAT2 (0.46) | AXLINSRP2RX3BTKGALR2 | |
| SCHEMBL4832431 | 0.79 | IDH2 (0.44) | AXLFGFR3CDK4CDK6CCNT1 | |
| SCHEMBL4836074 | 0.78 | EHMT2 (0.49) | AXLFGFR3CDK4CCND1KCNH2 | |
| SCHEMBL5550587 | 0.78 | GALR1 (0.48) | AXLCDK4CCND1INSRKCNH2 | |
| SCHEMBL5441794 | 0.77 | GALR1 (0.44) | AXLFGFR3KCNH2BCL6GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |