Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 4/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820022 | 0.86 | CCNA2 (0.42) | AXLCCNA2CDK2CCNA1IDH2 | |
| SCHEMBL4839029 | 0.85 | GALR1 (0.46) | CDK2FGFR3CDK4EHMT2 | |
| SCHEMBL5030770 | 0.85 | IDH2 (0.47) | AXLMEN1BLMKMT2AIDH2 | |
| SCHEMBL6270071 | 0.82 | AXL (0.40) | AXLBTKABL1BCRFGFR3 | |
| SCHEMBL27628454 | 0.77 | TERT (0.43) | NPC1RAB9AGAASMN1; SMN2JAK2 | |
| SCHEMBL5038282 | 0.76 | IDH2 (0.48) | AXLMEN1BLMKMT2AIDH2 | |
| SCHEMBL4836074 | 0.74 | EHMT2 (0.49) | AXLCDK2FGFR3CDK4EHMT2 | |
| SCHEMBL14300022 | 0.74 | IDH2 (0.50) | AXLCCNA2CDK2CCNA1BTK | |
| SCHEMBL5550587 | 0.74 | GALR1 (0.48) | AXLCDK2ALDH1A1SMN1; SMN2CDK4 | |
| SCHEMBL5441794 | 0.74 | GALR1 (0.44) | AXLFGFR3EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |