Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 10/20 | 0.42 |
| ▸ | CDK2 | P24941 | 10/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 10/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | CCND3 | P30281 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 4/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916773 | 0.86 | AXL (0.40) | CCNA2CDK2CCNA1IDH2CDK4 | |
| SCHEMBL4839029 | 0.85 | GALR1 (0.46) | CDK2CDK4 | |
| SCHEMBL5032214 | 0.85 | IDH2 (0.52) | CCNA2CDK2CCNA1IDH2AXL | |
| SCHEMBL6270071 | 0.82 | AXL (0.40) | CDK4CCND3AXL | |
| SCHEMBL6231142 | 0.76 | MAP4K4 (0.41) | PIM1AXLSLC2A1NOS3NOS1 | |
| SCHEMBL5038282 | 0.76 | IDH2 (0.48) | IDH2AXL | |
| SCHEMBL14300022 | 0.74 | IDH2 (0.50) | CCNA2CDK2CCNA1IDH2CCND3 | |
| SCHEMBL4836074 | 0.74 | EHMT2 (0.49) | CDK2CDK4AXL | |
| SCHEMBL5550587 | 0.74 | GALR1 (0.48) | CDK2CDK4AXL | |
| SCHEMBL5441794 | 0.74 | GALR1 (0.44) | AXLPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |