Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120468 | 0.85 | UGT2B7 (0.55) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL7514315 | 0.85 | UGT2B7 (0.55) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL12327035 | 0.84 | ALOX5 (0.61) | CYP1A2TSHR | |
| SCHEMBL2611790 | 0.81 | UGT2B7 (0.50) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL20168275 | 0.81 | UGT2B7 (0.50) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL15279347 | 0.80 | UGT2B7 (0.49) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL6934379 | 0.80 | UGT2B7 (0.49) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL5267799 | 0.80 | UGT2B7 (0.49) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL5266035 | 0.80 | UGT2B7 (0.49) | UGT2B7MMP9AOC3ADRA2AADRA2B | |
| SCHEMBL8318283 | 0.79 | UGT2B7 (0.45) | UGT2B7MMP9AOC3ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069115-B1 | PROCESS FOR PRODUCING OXAZOLIDIN-2-ONE DERIVATIVES | DAISO CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6271388-B1 | REACTING A 1,3-DIOXOLAN-2-ONE DERIVATIVE AND A CARBAMATE DERIVATIVE OR AN UREA DERIVATIVE IN THE PRESENCE OF A FLUORIDE SALT. | DAISO CO., LTD. (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-1069115-A1 | PROCESS FOR PRODUCING OXAZOLIDIN-2-ONE DERIVATIVES | DAISO CO., LTD. (JP) | 2001-01-17 | — | — | EP | disclosed |