Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.34 |
| ▸ | CCR10 | P46092 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268521 | 0.93 | P2RY12 (0.37) | HPGDHRH3GAAP2RY12CCR10 | |
| SCHEMBL3946841 | 0.86 | AOC3 (0.40) | HPGDAOC3 | |
| SCHEMBL6269247 | 0.81 | ALDH1A1 (0.41) | HRH3GAA | |
| SCHEMBL3948304 | 0.79 | AOC3 (0.41) | AOC3 | |
| SCHEMBL3953803 | 0.78 | AOC3 (0.40) | AOC3 | |
| SCHEMBL3945115 | 0.77 | AOC3 (0.40) | GAAAOC3 | |
| SCHEMBL6268525 | 0.76 | MMP3 (0.38) | HPGDGAAP2RY12CCR10 | |
| SCHEMBL3947613 | 0.72 | AOC3 (0.38) | AOC3 | |
| SCHEMBL3952829 | 0.69 | ALDH1A1 (0.46) | HRH3AOC3 | |
| SCHEMBL3952251 | 0.68 | AOC3 (0.40) | AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567509-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-08-31 | — | — | EP | claimed |
| WO-2004048351-A2 | BIPHENYL COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-10 | — | — | WO | claimed |