⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967397 | 1.00 | — | — | |
| SCHEMBL20838931 | 0.91 | SHBG (0.54) | — | |
| SCHEMBL2532059 | 0.91 | CPN1 (0.41) | — | |
| SCHEMBL17731364 | 0.91 | SHBG (0.54) | — | |
| SCHEMBL2308188 | 0.91 | SHBG (0.54) | — | |
| SCHEMBL13278433 | 0.91 | CYP2C9 (0.44) | — | |
| SCHEMBL3509472 | 0.91 | CYP2C9 (0.47) | — | |
| SCHEMBL6656137 | 0.89 | CPN1 (0.40) | — | |
| Cyclohexane SCHEMBL253223 | 0.89 | CYP2C9 (0.50) | — | |
| Cyclohexane SCHEMBL6631080 | 0.89 | CYP2C9 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109909-B1 | GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY | THERATECHNOLOGIES INC (CA) | 2005-11-30 | — | — | EP | disclosed |
| US-20040171534-A1 | GRF analogs with increased biological potency | THERATECHNOLOGIES, INC. (CA) | 2004-09-02 | — | — | US | disclosed |
| US-6458764-B1 | CHIMERIC FATTY BODY-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY, THEIR APPLICATION AS ANABOLIC AGENTS AND IN THE DIAGNOSIS AND TREATMENT OF GROWTH HORMONE DEFICIENCIES. THE CHIMERIC FATTY BODY-GRF ANALOGS INCLUDE AN HYDROPHOBIC MOIETY | THERATECHNOLOGIES INC. (CA) | 2002-10-01 | — | — | US | disclosed |