Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 5/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967397 | 0.91 | — | — | |
| SCHEMBL6270743 | 0.91 | — | — | |
| SCHEMBL20838931 | 0.83 | SHBG (0.54) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL17731364 | 0.83 | SHBG (0.54) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL2308188 | 0.83 | SHBG (0.54) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL3509472 | 0.83 | CYP2C9 (0.47) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL13278433 | 0.83 | CYP2C9 (0.44) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL5368097 | 0.82 | CPB2 (0.40) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL6656137 | 0.82 | CPN1 (0.40) | CPN1CPB2CYP2C9CYP2C19HIF1A | |
| SCHEMBL31109132 | 0.82 | CPN1 (0.39) | CPN1CPB2CYP2C9CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039477-B2 | Substituted pyrazolo[3,4-d]pyrimidin-4-one compounds as phosphodiesterase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-10-18 | — | — | US | disclosed |