Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9381631 | 0.75 | LMNA (0.43) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL1954252 | 0.75 | CCR1 (0.43) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL3947560 | 0.72 | CCR1 (0.36) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL747234 | 0.71 | PDGFRB (0.41) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL22116639 | 0.68 | KDM4E (0.36) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL4470663 | 0.68 | PDE10A (0.45) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL7950881 | 0.68 | KDM4E (0.41) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL22116784 | 0.68 | — | — | |
| SCHEMBL11212949 | 0.68 | KDM4E (0.44) | LMNACYP3A4HTTCCR1CCR5 | |
| SCHEMBL22116434 | 0.67 | MEN1 (0.38) | LMNACYP3A4HTTCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005103683-A1 | QUANTITATIVE METHOD OF DETERMINING BERYLLIUM OR A COMPOUND THEREOF IN A SAMPLE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-11-03 | — | — | WO | disclosed |