SCHEMBL6270903

SCHEMBL6270903

CCCC[Si](CCCOC(C)=O)(OC)OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
TSHR P16473 4/20 0.39
FAAH O00519 1/20 0.39
ATM Q13315 1/20 0.38
ACHE P22303 7/20 0.38
NAAA Q02083 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HPGD P15428 1/20 0.36
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
HTR1A P08908 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRM3 P20309 1/20 0.35
TBXA2R P21731 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3502570 0.83 TSHR (0.62) ALDH1A1TSHRFAAHATMACHE
SCHEMBL6267179 0.82 DGKA (0.47) ALDH1A1FAAHATMACHENAAA
SCHEMBL6151933 0.80 TSHR (0.66) ALDH1A1TSHRATMACHEHSD17B10
Acetic Acid Butyl Ester SCHEMBL9788282 0.78 ALDH1A1 (0.90) ALDH1A1TSHRFAAHATMNAAA
Acetic Acid Butyl Ester SCHEMBL28960923 0.77 ALDH1A1 (1.00) ALDH1A1TSHRFAAHATMNAAA
Acetic Acid Butyl Ester SCHEMBL1350194 0.77
Acetic Acid Butyl Ester SCHEMBL8026335 0.77 ALDH1A1 (1.00) ALDH1A1TSHRFAAHATMNAAA
Acetic Acid Butyl Ester SCHEMBL28984633 0.77 ALDH1A1 (1.00) ALDH1A1TSHRFAAHATMNAAA
Acetic Acid Butyl Ester SCHEMBL14969 0.77
Acetic Acid Butyl Ester SCHEMBL10950974 0.77 ALDH1A1 (0.72) ALDH1A1TSHRFAAHATMNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005103061-A1 METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS DOW CORNING TORAY CO., LTD. (JP) 2005-11-03 WO disclosed