Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 12/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30258242 | 0.85 | AR (0.42) | TNFRSF1AMAPTRXFP1KMT2AL3MBTL1 | |
| SCHEMBL6091784 | 0.82 | LMNA (0.58) | TNFRSF1AERN1MAPTRXFP1SLC6A9 | |
| SCHEMBL6265934 | 0.81 | MAPT (0.58) | TNFRSF1AERN1MAPTRXFP1MEN1 | |
| SCHEMBL6271609 | 0.79 | CYP1A2 (0.56) | TNFRSF1AERN1MAPTRXFP1SLC6A9 | |
| SCHEMBL11473280 | 0.78 | TNFRSF1A (0.53) | TNFRSF1AERN1MAPTRXFP1MEN1 | |
| SCHEMBL111283 | 0.77 | HTR1A (0.47) | TNFRSF1AMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6092496 | 0.74 | LMNA (0.46) | TNFRSF1AERN1MAPTRXFP1SLC6A9 | |
| SCHEMBL6040595 | 0.74 | LMNA (0.46) | TNFRSF1AERN1MAPTRXFP1SLC6A9 | |
| SCHEMBL6111378 | 0.74 | TNFRSF1A (0.69) | TNFRSF1AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL6091939 | 0.73 | TNFRSF1A (0.48) | TNFRSF1AERN1MAPTRXFP1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100301-A1 | 2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |