Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264420 | 0.87 | ALDH1A1 (0.45) | ALDH1A1RAB9ACYP1A2TSHRLMNA | |
| SCHEMBL6266229 | 0.85 | ALDH1A1 (0.44) | ALDH1A1RAB9ACYP1A2TSHRKMT2A | |
| SCHEMBL6025900 | 0.80 | KDM4E (0.52) | ALDH1A1KDM4ECXCR4TP53POLB | |
| Hydrochloric Acid SCHEMBL29740742 | 0.79 | KDM4E (0.54) | ALDH1A1KDM4ECXCR4TP53POLB | |
| SCHEMBL19597688 | 0.78 | POLB (0.59) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL1054071 | 0.77 | CXCR4 (0.66) | ALDH1A1KDM4ECXCR4CYP1A2LMNA | |
| SCHEMBL31426439 | 0.77 | CXCR4 (0.66) | ALDH1A1KDM4ECXCR4CYP1A2LMNA | |
| SCHEMBL31058796 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KDM4ERAB9ACYP1A2TSHR | |
| SCHEMBL5907863 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4ECXCR4LMNAMAPT | |
| SCHEMBL6279414 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4ECXCR4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056771-B1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-11-30 | — | — | EP | disclosed |
| EP-1056771-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043699-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 1999-09-02 | — | — | WO | disclosed |