Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6264420 | 0.98 | ALDH1A1 (0.45) | ALDH1A1TSHRCYP1A2LTA4HPTGS2 | |
| SCHEMBL6270956 | 0.85 | ALDH1A1 (0.47) | ALDH1A1TSHRCYP1A2L3MBTL1KMT2A | |
| SCHEMBL14058727 | 0.79 | HRH3 (0.55) | ALDH1A1CYP1A2HRH3SIGMAR1 | |
| SCHEMBL3939455 | 0.79 | HRH3 (0.55) | ALDH1A1CYP1A2HRH3SIGMAR1 | |
| SCHEMBL31058796 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL868571 | 0.77 | HRH3 (0.56) | ALDH1A1CYP1A2HRH3SIGMAR1 | |
| SCHEMBL30732408 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL12055882 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRCYP1A2CYP2C19MAPK1 | |
| SCHEMBL3161186 | 0.75 | CYP2C19 (0.65) | ALDH1A1TSHRCYP1A2L3MBTL1CYP2C19 | |
| SCHEMBL6660238 | 0.75 | LTA4H (0.48) | ALDH1A1TSHRCYP1A2LTA4HPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056771-B1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-11-30 | — | — | EP | disclosed |
| EP-1056771-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043699-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 1999-09-02 | — | — | WO | disclosed |