Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.60 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.60 |
| ▸ | GNPAT | O15228 | 1/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | GGH | Q92820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14310838 | 0.90 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL13946267 | 0.89 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1533825 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL6270974 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL27460563 | 0.86 | NOD1 (0.65) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL26382212 | 0.86 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL17384133 | 0.85 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL11961967 | 0.85 | FOLH1 (0.60) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL13840849 | 0.85 | FOLH1 (0.62) | FOLH1NAALAD2RIMKLAGNPATNOD1 | |
| SCHEMBL21360278 | 0.84 | FOLH1 (0.58) | FOLH1NAALAD2RIMKLAGNPATNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10415040-B2 | Nucleic acid amphiphiles and nanostructures | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-09-17 | — | — | US | disclosed |
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10415040-B2 | Nucleic acid amphiphiles and nanostructures | EWSR1, ANXA4, POLRMT | FOLH1 1001/4885NAALAD2 2991/4885RIMKLA 3775/4885 |
| US-20170218367-A1 | NUCLEIC ACID AMPHIPHILES AND NANOSTRUCTURES | EWSR1, ANXA4, POLRMT | FOLH1 1001/4885NAALAD2 2991/4885RIMKLA 3775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.