Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.65 |
| ▸ | HSP90AB1 | P08238 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TDP2 | O95551 | 1/20 | 0.65 |
| ▸ | FGB | P02675 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4729413 | 0.85 | MEN1 (0.70) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL6268423 | 0.80 | MEN1 (0.47) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Phosphoric Acid SCHEMBL11544230 | 0.80 | MEN1 (0.62) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Quinocide SCHEMBL157174 | 0.80 | MEN1 (1.00) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Quinocide SCHEMBL29720457 | 0.80 | MEN1 (1.00) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Quinocide SCHEMBL707955 | 0.79 | HSP90AA1 (1.00) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Quinocide SCHEMBL30823571 | 0.79 | HSP90AA1 (1.00) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Quinocide SCHEMBL28060369 | 0.79 | HSP90AA1 (1.00) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL5080647 | 0.78 | MAOA (0.66) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 | |
| Pyrophosphoric Acid SCHEMBL11544226 | 0.77 | MEN1 (0.59) | MEN1KMT2AHSP90AA1HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606263-A1 | RING-SUBSTITUTED 8-AMINOQUINOLINE DERIVATIVES AS ANTIMALARIAL AGENTS | Council of Scientific and Industrial Research (IN) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004085402-A1 | RING-SUBSTITUTED 8-AMINOQUNOLINE DERIVATES AS ANTIMALARIAL AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-10-07 | — | — | WO | disclosed |