Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NAMPT | P43490 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908186 | 0.91 | CYP19A1 (0.61) | ALDH1A1MAPK1HSD17B10CYP19A1LMNA | |
| SCHEMBL10205710 | 0.87 | ALDH1A1 (0.66) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL10462538 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL19554432 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL20946438 | 0.83 | CYP19A1 (0.69) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL26154030 | 0.83 | CA12 (0.71) | ALDH1A1CYP19A1KMT2AMEN1NAMPT | |
| SCHEMBL1287434 | 0.83 | ALDH1A1 (0.70) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL5960116 | 0.83 | MEN1 (0.73) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL28113182 | 0.83 | CA1 (0.73) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A | |
| SCHEMBL4662845 | 0.83 | KEAP1 (0.76) | ALDH1A1MAPK1HSD17B10CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245561-B1 | N-SUBSTITUTED BENZYL OR PHENYL AROMATIC SULFAMIDES COMPOUNDS AND THE USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2005-12-28 | — | — | EP | disclosed |
| CN-1172908-C | N-substituted benzyl or phenyl aromatic amide compound and its use | �й���ѧԺ�Ϻ�ҩ���о��� | 2004-10-27 | — | — | CN | disclosed |
| US-6605635-B1 | Prevention and treatment of cardiac arrhythmia; condensation of aromatic sulfochloride with p-hydroxybenzylamine followed by mannich reaction | SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCE (CN) | 2003-08-12 | — | — | US | disclosed |
| EP-1245561-A1 | N-SUBSTITUTED BENZYL OR PHENYL AROMATIC SULFAMIDES COMPOUNDS AND THE USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2002-10-02 | — | — | EP | disclosed |
| CN-1299813-A | N-substituted benzyl or phenyl aromatic amide compound and its use | SHANGHAI INST OF PHARMACOLOGY (CN) | 2001-06-20 | — | — | CN | disclosed |