Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933440 | 0.79 | BCAT2 (0.44) | ALDH1A1MAPTLMNAPKMBCAT2 | |
| SCHEMBL6277250 | 0.78 | POLB (0.50) | ALDH1A1CYP1A2CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL3459611 | 0.77 | HCAR2 (0.38) | ALDH1A1KDM4EMAPTPKMMEN1 | |
| SCHEMBL6271882 | 0.76 | ALDH1A1 (0.54) | ALDH1A1IKBKBBTKKDM4EMAPT | |
| SCHEMBL1659093 | 0.74 | ALDH1A1 (0.36) | ALDH1A1CYP2C9KDM4ELMNABCAT2 | |
| SCHEMBL27592421 | 0.73 | MAPT (0.47) | ALDH1A1IKBKBKDM4EMAPTLMNA | |
| SCHEMBL69825 | 0.71 | GRIA4 (0.50) | ALDH1A1CYP2C9KDM4EMAPTLMNA | |
| SCHEMBL5154551 | 0.71 | ALDH1A1 (0.49) | ALDH1A1KDM4EPKMRXFP1KMT2A | |
| SCHEMBL14100164 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KDM4EPKMRXFP1KMT2A | |
| SCHEMBL2157777 | 0.69 | PTPN1 (0.44) | ALDH1A1KDM4EMAPTLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |