Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | CPA2 | P48052 | 2/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FCER2 | P06734 | 5/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271906 | 1.00 | MMP2 (0.44) | MMP2MMP3MMP7CPA1CPA2 | |
| SCHEMBL6274525 | 0.89 | CPA1 (0.42) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6274532 | 0.89 | CPA1 (0.42) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6274169 | 0.88 | CPA1 (0.44) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6274176 | 0.88 | CPA1 (0.44) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6271544 | 0.87 | CPA1 (0.43) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6273702 | 0.87 | CPA1 (0.45) | MMP2MMP7CPA1CPA2CPA4 | |
| SCHEMBL6273707 | 0.87 | CPA1 (0.45) | MMP2MMP7CPA1CPA2CPA4 | |
| SCHEMBL6271538 | 0.87 | CPA1 (0.43) | CPA1CPA2CPA4CPB1ACE2 | |
| SCHEMBL6273826 | 0.86 | CTSL (0.45) | CPA1CPA2CPA4CPB1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | claimed |
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |