SCHEMBL6271965

SCHEMBL6271965

C=CCc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
CYP3A4 P08684 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALOX12 P18054 1/20 0.50
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
THRB P10828 3/20 0.42
FFAR1 O14842 1/20 0.41
PTGS1 P23219 1/20 0.41
RAB9A P51151 3/20 0.40
SRD5A2 P31213 1/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978551 0.93 ALDH1A1 (0.57) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL16340149 0.84 ALDH1A1 (0.55) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL4284968 0.83 KMT2A (0.62) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL11013802 0.83 KMT2A (0.58) SMN1; SMN2CYP3A4ALDH1A1TSHRKMT2A
SCHEMBL7157961 0.82 ALDH1A1 (0.57) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL11378484 0.81 CYP3A4 (0.50) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL9860302 0.80 ALDH1A1 (0.55) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL311913 0.80 THRB (0.64) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL9861011 0.80 ALDH1A1 (0.55) SMN1; SMN2CYP3A4ALDH1A1TP53ALOX15
SCHEMBL4207477 0.80 KMT2A (0.57) KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1274763-B1 PROCESS FOR REDISTRIBUTION OF POLYCARBONATE GEN ELECTRIC (US) 2005-07-20 EP disclosed
EP-1274763-A1 PROCESS FOR REDISTRIBUTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-15 EP disclosed
US-6492485-B1 THE APPLICATION RELATES TO METHODS FOR PRODUCING A POLYCARBONATE RESIN HAVING A NARROWED MOLECULAR WEIGHT DISTRIBUTION, SPECIFICALLY, THE APPLICATION RELATES TO THE USE OF A REDISTRIBUTION CATALYST AND A FEEDBACK LOOP CONTROL GENERAL ELECTRIC COMPANY 2002-12-10 US disclosed
WO-2001077206-A1 PROCESS FOR REDISTRIBUTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2001-10-18 WO disclosed
EP-0595608-B1 Redistribution of organic polycarbonate compositions GEN ELECTRIC (US) 1997-07-16 EP disclosed
US-5414057-A Redistribution of organic polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1995-05-09 US disclosed
EP-0595608-A1 Redistribution of organic polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1994-05-04 EP disclosed