⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937262 | 0.73 | — | — | |
| SCHEMBL9021872 | 0.72 | — | — | |
| SCHEMBL647844 | 0.70 | — | — | |
| SCHEMBL15361 | 0.70 | — | — | |
| SCHEMBL10975 | 0.67 | — | — | |
| SCHEMBL9574541 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL83309 | 0.67 | — | — | |
| SCHEMBL83728 | 0.67 | — | — | |
| SCHEMBL1398293 | 0.67 | — | — | |
| SCHEMBL9938132 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458742-A1 | Fluorinated silicone polymers | CIBA-GEIGY AG (CH) | 1991-11-27 | — | — | EP | claimed |
| US-5057377-A | Polyurethane and coplymers; oil and water repellent coatings; textiles | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | claimed |
| JP-4249515-A | — | — | None | — | — | JP | disclosed |
| EP-1000620-B1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBITORS | TAIHO PHARMACEUTICAL CO LTD (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6166036-A | Lp(a)-lowering agent and apolipoprotein (a) formation suppressing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-1000620-A1 | Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5145865-A | Fatty acid, cholesterol synthesis inhibitors; enzyme inhibitors; antilipemic agents | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| JP-H04249515-A | FLUORINATED SILICONE POLYMER | CIBA GEIGY AG | 1992-09-04 | — | — | JP | disclosed |
| EP-0458742-A1 | Fluorinated silicone polymers | CIBA-GEIGY AG (CH) | 1991-11-27 | — | — | EP | disclosed |
| US-5057377-A | Polyurethane and coplymers; oil and water repellent coatings; textiles | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |