Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 3/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | CYP24A1 | Q07973 | 6/20 | 0.54 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.54 |
| ▸ | CYP27A1 | Q02318 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596909 | 0.89 | METAP1 (0.65) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL8874844 | 0.89 | METAP1 (0.65) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL4621871 | 0.86 | CYP24A1 (0.68) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL6272211 | 0.85 | METAP1 (0.68) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL9854934 | 0.84 | METAP1 (0.60) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL15617638 | 0.84 | METAP1 (0.70) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL14306761 | 0.82 | METAP1 (0.72) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL6278666 | 0.82 | METAP1 (0.57) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL8596536 | 0.82 | METAP1 (0.69) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 | |
| SCHEMBL8874769 | 0.82 | METAP1 (0.69) | METAP1CYP19A1CYP24A1CYP26A1CYP27A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097093-A1 | SLEEP INDUCING COMPOUNDS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-4443626-A | ANTIINFLAMMATORY, ANTIALLERGENS, ANALGESICS, ANTICOAGULANTS, ANTIPRETICS, OR ANTICHOLESTEROL AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1984-04-17 | — | — | US | disclosed |