SCHEMBL6272633

SCHEMBL6272633

CC(=O)CC(C(C)=O)(C(C)=O)C(C)=O.[Pt]

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
TRPA1 O75762 1/20 0.35
KDM4E B2RXH2 1/20 0.31
KDM6B O15054 1/20 0.31
KDM5C P41229 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
LMNA P02545 1/20 0.30
SLC15A2 Q16348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649993 0.97 ALDH1A1 (0.39) ALDH1A1TDP1TRPA1KDM4EKDM6B
SCHEMBL11743715 0.94 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1KDM4EKDM6B
SCHEMBL2855901 0.76 MGAM (0.39) ALDH1A1KDM4EKDM6BKDM5CEGLN1
SCHEMBL27640703 0.75 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL10571434 0.71 ALDH1A1 (0.39) ALDH1A1TDP1TRPA1LMNASLC15A2
SCHEMBL16662440 0.69 ALDH1A1 (0.44) ALDH1A1TDP1TRPA1LMNASLC15A2
SCHEMBL13240553 0.69 HMGCR (0.41) ALDH1A1TDP1TRPA1LMNASLC15A2
SCHEMBL27870232 0.69 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1LMNASLC15A2
SCHEMBL10001246 0.69 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1LMNASLC15A2
SCHEMBL9015652 0.69 ALDH1A1 (0.37) ALDH1A1TDP1TRPA1LMNASLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005073341-A1 DUAL EMITTING DYADS OF HEAVY METAL COMPLEXES AS BROAD BAND EMITTERS FOR ORGANIC LEDS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2005-08-11 WO disclosed