Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 5/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HAT1 | O14929 | 3/20 | 0.36 |
| ▸ | EP300 | Q09472 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272488 | 0.93 | F2 (0.37) | ADRB1ADRB3SLC2A1HAT1EP300 | |
| SCHEMBL6279664 | 0.91 | ADAMTS4 (0.37) | HAT1EP300L3MBTL1KMT2AADAMTS4 | |
| SCHEMBL6276815 | 0.89 | GAA (0.36) | HAT1EP300L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL6272911 | 0.88 | KMT2A (0.42) | ADRB3AURKARPS6KB1SLC2A1HAT1 | |
| SCHEMBL6272839 | 0.83 | KMT2A (0.42) | ADRB1ADRB3SLC2A1KMT2A | |
| SCHEMBL6267905 | 0.83 | ADRB3 (0.39) | ADRB1ADRB3SLC2A1HAT1EP300 | |
| SCHEMBL6282221 | 0.82 | KMT2A (0.39) | ADRB1ADRB3SLC2A1ADRB2KMT2A | |
| SCHEMBL6272946 | 0.81 | NR1H3 (0.36) | ADRB1ADRB3AURKARPS6KB1L3MBTL1 | |
| SCHEMBL6272444 | 0.81 | ADRB3 (0.43) | ADRB1ADRB3KMT2A | |
| SCHEMBL6273366 | 0.81 | AKR1C3 (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |