Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.37 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272839 | 0.92 | KMT2A (0.42) | KMT2ASLC2A1ADRB1ACP1PTPN12 | |
| SCHEMBL6272911 | 0.90 | KMT2A (0.42) | KMT2ASLC2A1ACP1PTPN12PTPN13 | |
| SCHEMBL6272444 | 0.89 | ADRB3 (0.43) | KMT2AADRB1ADRB3LRRK2AKR1C3 | |
| SCHEMBL6273366 | 0.89 | AKR1C3 (0.42) | KMT2ALRRK2AKR1C3 | |
| SCHEMBL6274430 | 0.88 | AKR1C3 (0.43) | KMT2ALRRK2AKR1C3 | |
| SCHEMBL6269797 | 0.88 | LRRK2 (0.49) | KMT2ASLC2A1ACP1PTPN12PTPN13 | |
| SCHEMBL6267515 | 0.88 | AKR1C3 (0.42) | KMT2ALRRK2AKR1C3 | |
| SCHEMBL6269313 | 0.82 | KMT2A (0.44) | KMT2AADRB3AKR1C3 | |
| SCHEMBL6273802 | 0.82 | SIRT2 (0.41) | KMT2AFFAR1ADAMTS4 | |
| SCHEMBL6272944 | 0.82 | ADRB1 (0.37) | KMT2ASLC2A1ADRB1ADRB3ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110981-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2005-11-24 | — | — | WO | disclosed |