SCHEMBL6272986

SCHEMBL6272986

CNc1ncnc2[nH]cnc12.CNc1ncnc2[nH]cnc12.[Zn]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
YTHDC1 Q96MU7 4/20 0.46
YTHDF2 Q9Y5A9 2/20 0.46
PDPK1 O15530 2/20 0.43
CSF1R P07333 1/20 0.37
XDH P47989 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
CYP2C19 P33261 1/20 0.36
HBB P68871 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
MAP4K4 O95819 1/20 0.35
HTT P42858 2/20 0.34
CYP1A2 P05177 2/20 0.33
HIF1A Q16665 1/20 0.33
LRRK2 Q5S007 1/20 0.32
ROCK1 Q13464 1/20 0.32
LMNA P02545 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
ADORA1 P30542 1/20 0.31
CDK2 P24941 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21913 0.98 YTHDC1 (0.47) YTHDC1YTHDF2PDPK1CSF1RXDH
SCHEMBL10918759 0.96 YTHDC1 (0.46) YTHDC1YTHDF2PDPK1CSF1RXDH
SCHEMBL30480243 0.85 YTHDC1 (0.36) YTHDC1YTHDF2PDPK1HTTCYP1A2
SCHEMBL405822 0.82 PDPK1 (0.34) YTHDC1YTHDF2PDPK1CSF1RHTT
SCHEMBL22892194 0.82 CSNK2A1 (0.33) YTHDC1YTHDF2PDPK1XDHHTT
SCHEMBL5628450 0.80 CYP1A2 (0.50) YTHDC1YTHDF2PDPK1ALDH1A1TP53
SCHEMBL30677338 0.79 PDPK1 (0.33) PDPK1XDHALDH1A1TP53HBB
SCHEMBL11591791 0.79 HTT (0.33) XDHALDH1A1TP53HBBHTT
SCHEMBL2116843 0.79 PDPK1 (0.33) PDPK1XDHALDH1A1TP53HBB
SCHEMBL9116343 0.78 HTT (0.32) XDHHTTCYP1A2HIF1ALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820608-B1 MULTICOLOR DIFFUSION TRANSFER PHOTOGRAPHIC FILM ELEMENTS POLAROID CORP (US) 2005-07-27 EP disclosed
EP-0820608-A1 MULTICOLOR DIFFUSION TRANSFER PHOTOGRAPHIC FILM ELEMENTS POLAROID CORPORATION (US) 1998-01-28 EP disclosed
WO-1997029406-A1 MULTICOLOR DIFFUSION TRANSFER PHOTOGRAPHIC FILM ELEMENTS POLAROID CORPORATION (US) 1997-08-14 WO disclosed
US-5571656-A Multicolor diffusion transfer photographic film elements POLROID CORPORATION (US) 1996-11-05 US disclosed