Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
| ▸ | PI4KA | P42356 | 2/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116843 | 1.00 | PDPK1 (0.33) | PDPK1HTTCYP3A4LMNAXDH | |
| SCHEMBL11591791 | 0.83 | HTT (0.33) | HTTCYP3A4LMNAXDHPI4KA | |
| SCHEMBL4242949 | 0.81 | EGFR (0.33) | HTTCYP3A4LMNAXDHPI4KA | |
| SCHEMBL9116343 | 0.81 | HTT (0.32) | HTTCYP3A4LMNAXDHPI4KA | |
| SCHEMBL160073 | 0.81 | CYP3A4 (0.35) | HTTCYP3A4LMNAXDHPI4KA | |
| SCHEMBL22892194 | 0.81 | CSNK2A1 (0.33) | PDPK1HTTCYP3A4LMNAXDH | |
| SCHEMBL21913 | 0.81 | YTHDC1 (0.47) | PDPK1HTTCYP3A4LMNAXDH | |
| SCHEMBL10918759 | 0.79 | YTHDC1 (0.46) | PDPK1HTTCYP3A4LMNAXDH | |
| SCHEMBL6272986 | 0.79 | YTHDC1 (0.46) | PDPK1HTTCYP3A4LMNAXDH | |
| SCHEMBL2938977 | 0.78 | MKNK1 (0.32) | HTTCYP3A4MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |