Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673493 | 0.80 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL10877627 | 0.80 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL15782878 | 0.80 | TRPM4 (0.47) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL9678351 | 0.79 | MEN1 (0.51) | MEN1KMT2ARAB9ANPC1MAPT | |
| Phosphoric Acid SCHEMBL9602526 | 0.77 | MEN1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL16131299 | 0.76 | MEN1 (0.60) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL27724708 | 0.76 | CYP2D6 (0.51) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL11233662 | 0.72 | TRPM4 (0.52) | KMT2AMAPTLMNAGAAPOLB | |
| SCHEMBL4971446 | 0.72 | ALOX15 (0.67) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9131462 | 0.71 | KMT2A (0.51) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005110391-A2 | COMPOUNDS FOR TREATING HUMAN PAPILLOMAVIRUS | UNIVERSITY OF MASSACHUSETTS (US) | 2005-11-24 | — | — | WO | disclosed |