Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271799 | 0.94 | SMPD1 (0.43) | CYP3A4SMPD1TSHRL3MBTL1LPAR1 | |
| SCHEMBL6271516 | 0.92 | CYP3A4 (0.45) | CYP3A4SMPD1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL6265924 | 0.88 | SMPD1 (0.34) | CYP3A4SMPD1L3MBTL1FDPS | |
| SCHEMBL6269585 | 0.86 | SMPD1 (0.47) | CYP3A4SMPD1L3MBTL1LPAR1LPAR3 | |
| SCHEMBL2049376 | 0.86 | CYP3A4 (0.46) | CYP3A4SMPD1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL6273519 | 0.84 | SMPD1 (0.44) | CYP3A4SMPD1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL1295608 | 0.82 | CYP3A4 (0.53) | CYP3A4SMPD1TSHRL3MBTL1LPAR1 | |
| SCHEMBL6271171 | 0.81 | SMPD1 (0.35) | CYP3A4SMPD1TSHRL3MBTL1FDPS | |
| SCHEMBL351162 | 0.80 | ADRB2 (0.39) | CYP3A4SMPD1TSHRCA1CA2 | |
| SCHEMBL6266756 | 0.80 | LPAR3 (0.40) | CYP3A4SMPD1L3MBTL1LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157055-B1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | CROMPTON CORP (US) | 2005-12-14 | — | — | EP | disclosed |
| US-6369156-B1 | CURABLE MIXTURE; AROMATIC POLYAMINE CONTAINING THIOETHER GROUP, PHOSPHATE ESTER, AND ALDEHYDE OR ALDEHYDE-FORMING COMPOUND; DISCOLORATION INHIBITION | VANTICO INC. | 2002-04-09 | — | — | US | disclosed |
| EP-1157055-A1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | Vantico AG (CH) | 2001-11-28 | — | — | EP | disclosed |
| EP-1097952-A1 | Polurethane/Polyurea-forming compositions | Vantico AG (CH) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000035983-A1 | THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS | VANTICO AG (CH) | 2000-06-22 | — | — | WO | disclosed |