SCHEMBL6273519

SCHEMBL6273519

CCCCC(OCCC)OP(=O)(OC(CCCC)OCCC)OC(CCCC)OCCC

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.44
CYP3A4 P08684 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
FDPS P14324 4/20 0.38
TSHR P16473 1/20 0.35
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LPAR1 Q92633 2/20 0.31
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6271516 0.92 CYP3A4 (0.45) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL6269585 0.90 SMPD1 (0.47) SMPD1CYP3A4L3MBTL1FDPSLPAR1
SCHEMBL6265924 0.88 SMPD1 (0.34) SMPD1CYP3A4L3MBTL1FDPS
SCHEMBL6268013 0.86 SMPD1 (0.46) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL6273302 0.84 CYP3A4 (0.45) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL6271799 0.82 SMPD1 (0.43) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL2521683 0.81 CYP3A4 (0.34) SMPD1CYP3A4L3MBTL1TSHR
SCHEMBL4444204 0.80 DNM1 (0.38) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL6273023 0.79 SMPD1 (0.47) SMPD1CYP3A4L3MBTL1FDPSTSHR
SCHEMBL2049376 0.78 CYP3A4 (0.46) SMPD1CYP3A4L3MBTL1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157055-B1 THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS CROMPTON CORP (US) 2005-12-14 EP disclosed
US-6369156-B1 CURABLE MIXTURE; AROMATIC POLYAMINE CONTAINING THIOETHER GROUP, PHOSPHATE ESTER, AND ALDEHYDE OR ALDEHYDE-FORMING COMPOUND; DISCOLORATION INHIBITION VANTICO INC. 2002-04-09 US disclosed
EP-1157055-A1 THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS Vantico AG (CH) 2001-11-28 EP disclosed
EP-1097952-A1 Polurethane/Polyurea-forming compositions Vantico AG (CH) 2001-05-09 EP disclosed
WO-2000035983-A1 THERMOSETTING POLY URETHANE/UREA-FORMING COMPOSITIONS VANTICO AG (CH) 2000-06-22 WO disclosed