Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.47 |
| ▸ | TYMP | P19971 | 1/20 | 0.47 |
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.46 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.46 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273371 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL11175481 | 0.94 | LGALS9 (0.54) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL11175487 | 0.94 | LGALS9 (0.54) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL11169728 | 0.92 | ALDH1A1 (0.51) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL27988153 | 0.92 | LGALS9 (0.53) | ALDH1A1HTTSYNJ2TYMPLGALS9 | |
| SCHEMBL9245476 | 0.91 | ALDH1A1 (0.49) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL26455064 | 0.91 | ALDH1A1 (0.49) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL9245472 | 0.91 | ALDH1A1 (0.49) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL20691410 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TDP1HTTMAPK1POLB | |
| SCHEMBL15267379 | 0.89 | ALDH1A1 (0.48) | ALDH1A1TDP1HTTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378369-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-03-29 | — | — | US | claimed |
| WO-2005075490-A2 | SYNTHESIS OF POLYSULFATED URONIC ACID GLYCOSIDES | IVAX CORPORATION (US) | 2005-08-18 | — | — | WO | disclosed |
| US-4378369-A | HYPOGLYCEMIC, ANTIDIABETIC | SANDOZ, INC. (US) | 1983-03-29 | — | — | US | disclosed |