Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5948392 | 0.87 | HSD17B10 (0.48) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL68064 | 0.87 | CYP3A4 (0.75) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL7743436 | 0.87 | CYP3A4 (0.75) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL31392414 | 0.87 | CYP3A4 (0.75) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL23909388 | 0.83 | CYP3A4 (0.50) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL5948911 | 0.82 | TSHR (0.48) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL7104820 | 0.80 | ESR1 (0.58) | CYP3A4MAPK1HSD17B10ESR1ESR2 | |
| SCHEMBL5948554 | 0.80 | CYP3A4 (0.46) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL5948713 | 0.78 | CYP3A4 (0.44) | CYP3A4MAPK1TSHRHSD17B10HPGD | |
| SCHEMBL5948552 | 0.77 | CYP3A4 (0.43) | CYP3A4MAPK1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182340-A | Molding materials having shorter gel time with aliphatic amine curing agents | THE DOW CHEMICAL COMPANY (US) | 1993-01-26 | — | — | US | claimed |
| EP-0379058-A2 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | THE DOW CHEMICAL COMPANY (US) | 1990-07-25 | — | — | EP | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | disclosed |
| WO-2005110460-A2 | DIAGNOSIS AND TREATMENT METHODS RELATED TO AGING, ESPECIALLY IN MUSCLE (14.1) | OHIO UNIVERSITY (US) | 2005-11-24 | — | — | WO | disclosed |
| EP-0386404-A2 | Liquid crystal/rigid rodlike polymer modified epoxy/vinyl ester resins | THE DOW CHEMICAL COMPANY (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0379058-A2 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | THE DOW CHEMICAL COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| EP-0351201-A2 | Non-shrinkable hybrid yarn | HOECHST CELANESE CORPORATION (US) | 1990-01-17 | — | — | EP | disclosed |