Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513821 | 0.84 | TSHR (0.62) | CYP3A4MAPK1TSHRALDH1A1PIK3CA | |
| SCHEMBL6273598 | 0.83 | CYP3A4 (0.60) | CYP3A4MAPK1TSHRALDH1A1CA12 | |
| SCHEMBL2935720 | 0.79 | AHR (0.48) | CYP3A4MAPK1TSHRALDH1A1CYP2A6 | |
| SCHEMBL7025147 | 0.78 | CYP2A6 (0.43) | TSHRALDH1A1PIK3CACYP2A6DPP4 | |
| SCHEMBL29807938 | 0.77 | ALDH1A1 (0.62) | CYP3A4TSHRALDH1A1PIK3CACYP2A6 | |
| SCHEMBL1022489 | 0.77 | ALDH1A1 (0.62) | CYP3A4TSHRALDH1A1PIK3CACYP2A6 | |
| SCHEMBL29802156 | 0.75 | CYP2A6 (0.67) | TSHRALDH1A1CYP2A6DPP4KDM4E | |
| SCHEMBL29883244 | 0.75 | CYP2A6 (0.67) | TSHRALDH1A1CYP2A6DPP4KDM4E | |
| SCHEMBL671133 | 0.75 | CYP2A6 (0.67) | TSHRALDH1A1CYP2A6DPP4KDM4E | |
| SCHEMBL18516201 | 0.75 | ALDH1A1 (0.59) | CYP3A4TSHRALDH1A1PIK3CACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |