SCHEMBL7104820

SCHEMBL7104820

Oc1ccc(-c2ccc(O)c(Cl)c2Cl)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.58
ESR2 Q92731 11/20 0.58
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
ALOX5 P09917 2/20 0.43
GYS1 P13807 1/20 0.40
HSD17B10 Q99714 1/20 0.39
PELI1 Q96FA3 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5309602 0.85 ESR1 (0.58) ESR1ESR2CA12CA1CA2
SCHEMBL28121322 0.82 AHR (0.59) ESR1ESR2CA12CA1CA2
SCHEMBL6273598 0.80 CYP3A4 (0.60) ESR1ESR2CA12CA1CA2
SCHEMBL31392414 0.74 CYP3A4 (0.75) ESR1ESR2CA12CA1CA2
SCHEMBL4893627 0.74 ESR1 (0.46) ESR1ESR2CA12CA1CA2
SCHEMBL7743436 0.74 CYP3A4 (0.75) ESR1ESR2CA12CA1CA2
SCHEMBL68064 0.74 CYP3A4 (0.75) ESR1ESR2CA12CA1CA2
SCHEMBL8647267 0.71 GYS1 (0.59) ESR1ESR2CA12CA1CA2
SCHEMBL4899922 0.71 ESR1 (0.64) ESR1ESR2CA12CA1CA2
SCHEMBL2279047 0.71 AHR (0.69) ESR1ESR2CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920395-B Copolymerization type aromatic polycarbonate and preparation method thereof 万华化学集团股份有限公司 2022-09-20 CN disclosed
CN-112920395-A Copolymerization type aromatic polycarbonate and preparation method thereof 万华化学集团股份有限公司 2021-06-08 CN disclosed
CN-1209393-C Method for treating polyarylene sulfide by-product salt PETROLEUM ENERGY CT JURDICAL I (JP) 2005-07-06 CN disclosed
CN-1500113-A Method of treating by-product salt yielded with polyarylene sulfide ���ŷ���ʯ�Ͳ�ҵ���Ի����� 2004-05-26 CN disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP disclosed
EP-0105090-A1 Polycarbonate composition GENERAL ELECTRIC COMPANY (US) 1984-04-11 EP disclosed
US-4358563-A MOLDING MATERIALS OF IMPROVED IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1982-11-09 US disclosed